2011 International PRRS Symposium
Final Program
Pre-Symposium Workshops-Friday, December 2nd
***Pre-symposium workshops are open and free to conference attendees***
NC-229 2011 Business and Scientific Meeting
NC229
Business Meeting:
1:00 XJ
Meng, opening remarks
1:05 Update
of NC229, Dr. David Benfield, Administrative Advisor
1:15
Election of new NC-229 officer
1:20 Update
from USDA-NIFA (Drs. Peter Johnson/Margo Holland)
NC229: Scientific Meeting:
“What works
& what questions still need to be answered to obtain PRRSV elimination and
control?”
1:30-1:55 European perspective
Dr. Hans Nauwynck, Laboratory
of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan,
Merelbeke, Belgium
1:55-2:20 Canadian perspective
Dr Leigh Rosengren, Canadian
Swine Veterinarian Association PRRSV Area Regional Control and Eradication
Coordinator.
2:20-2:45 US perspective
Dr. Scott Dee, Director
of Research, Pipestone Veterinary Clinic, Pipestone, MN.
2:45: Jane Christopher-Hennings, closing comments
Novel Vaccine and Vaccination Strategy
Workshop
(Sponsored by USDA PRRS CAP2,
Director, Bob Rowland)
3:00 pm to 4:45 pm, December 2, 2011,
Chicago Downtown Marriott
Workshop
Co-chairs: X.J. Meng,
and Bob Rowland
3:00 – 3:30 PM
Luis Enjuanes, PhD, Professor,
Centro Nacional de Biotecnología, CSIC, Campus Universidad Autónoma de Madrid,
Spain.
Title: Novel vaccines against SARS-Coronaviruses
3:30 – 4:00 PM
Chris Roberts, PhD, Associate
Professor, Center for Molecular Medicine and Infectious Diseases, Virginia
Tech, Blacksburg, VA
Title: Co-presentation of bioactive membrane-bound
immunomodulators on viral vaccines to enhance vaccine immunogenicity and
efficacy: a novel vaccine platform targeting enveloped viruses
4:00 – 4:30 PM
XiaoPing Zhu, PhD, Associate
Professor, University of Maryland, College Park, MD
Title: Efficient mucosal vaccination against viral
infections through neonatal Fc receptor (FcRn)
4:30 – 4:45 PM
Q/A and Panel Discussions
2011 International PRRS Symposium
Draft Program
Friday, December 2nd
2011 International PRRS Symposium Opening Session
Co-Chairs: X.J. Meng and Lisa Becton
17:00 Welcome. X. J. Meng, Chair – 2011 Intl PRRS Symposium
17:10 Keynote Presentation: Dr. Christopher Walker, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio. Topic: Immunity and Control of Chronic Hepatitis C Virus Infection
18:15 Reception and cash bar
Poster Session until 20:00
Saturday, December 3th
8:00 Keynote Presentation: Dr. Asit Pattnaik, University of Nebraska. Topic: Porcine Reproductive and Respiratory Syndrome Virus Proteins in Infection and Immunity
Session l: Molecular Biology, Moderators: Eric Vaughn & Carl Gagnon
8:40 ISG15 and PRRSV nsp2 OTU domain mediated deISGylation function.
Ying Fang, South Dakota State University, Brookings, SD.
9:00 Lipid-anchored membrane association of the PRRS virus GP4 glycoprotein and co-localization with CD163 in lipid rafts.
Dongwan Yoo, University of Illinois at Urbana-Champaign.
9:20 Comparative microRNAs and messenger RNAs expression
analyses in PRRSV-infected MARC-145 cells and in lung tissues of pigs experimentally infected with PRRSV.
Yaowei Huang, Virginia Polytechnic Institute & State University, Blacksburg, VA.
9:40 Coffee break and Poster session
Session II: Vaccine & Immunity, Moderators: Cinta Prieto & Roman Pogranichniy
10:40 Different cytokine patterns in ex vivo stimulated PBMC are related to the PRRSV isolate.
Luca Ferrari, University of Parma, Italy.
11:00 Antiviral Regulation Underlying the Activation Status of Porcine Monocytic Innate Immune Cells.
Yongming Sang, Kansas State University, Manhattan, KS.
11:20 Attenuation of a Virulent North American PRRS Virus Isolate on CD163-expressing Cell Lines, and Demonstration of Efficacy against a Heterologous Challenge.
Jay Calvert, Pfizer Animal Health, Kalamazoo, MI.
11:40 PRRS Host Genome Consortium Database: Development of a System of Data Storage and Sharing for a Multi-Organizational Group.
Eric Fritz, Iowa State University, Ames, IA.
12:00 Lunch buffet
Session III: Virus-Host Interaction, Moderators: Yanjin Zhang & Andrea Wilson
13:00 The recombination between two strains of PRRSV in vivo results in the generation of recombinant virus with higher pathogenicity.
Hanchun Yang, China Agricultural University, Beijing, China.
13:20 Comparison of immune transcriptome response following infection with PRRSV, PCV2 and SIV.
Laura Miller, National Animal Disease Center-USDA-ARS, Ames, IA.
13:40 Interaction of PRRSV genotype I and II with plasmacytoid dendritic cells.
Artur Summerfield, Institute for Virology and Immunoprophylaxis, Mittelhausern, Switzerland.
14:00 Non-structural proteins 1? and 1? down modulate tumor necrosis factor-alpha expression after porcine reproductive and respiratory syndrome virus infection.
Sakthivel Subramanian, University of Nebraska-Lincoln.
14:20 Characterization of Asian Highly Pathogenic Strains of Type 2 PRRSV.
Kay Faaberg, National Animal Disease Center-USDA-ARS, Ames, IA.
14:40 Break (refreshments in the poster area)
Session IV : Epidemiology, Heterogeneity, and Evolution, Moderators: William Laegreid & Fred Leung
15:10 Association between PRRSV ORF5 genetic distance and differences in space, time, ownership, and animal sources among commercial pig herds.
Thomas Rosendal, University of Guelph, Canada.
15:30 Detection of PRRSV antibodies in oral fluid specimens using a commercial PRRSV serum antibody ELISA.
Apisit Kittawornrat, Iowa State University, Ames, IA.
15:50 Novel PRRSV ORF5a protein is not immunoprotective but drives GP5 Glycosylation.
Sally Robinson, University of Minnesota, Roseville, MN.
16:10 A high resolution characterization of spatial dissemination of Type 2 PRRSV in North America.
Mang Shi, The University of Hong Kong.
16:30 Assessment of the economic impact of porcine reproductive and respiratory syndrome virus on U.S. pork producers.
Derald Holtkamp, Iowa State University, Ames, IA.
16:50 Closing Remarks,
Jane Christopher-Hennings, Scientific Program Chair
17:00 Adjourn